E-ISSN 2229-7723 | ISSN 0976-9234
 
2022, Vol: 13, Issue: 2
13/2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article 


Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair.

Abstract
Objectives: Pseudomonas aeruginosa continues to be the most common pathogen in the nosocomial settings. This organism shows the high level of resistance against various groups of antibiotics. Therefore, this study investigates the association between the Class 1 integron and multidrug-resistant P. aeruginosa bacterium isolated from burn and wound infections. Materials and Methods: A total of 184 isolates of P. aeruginosa were collected from nonrepetitive burn and wound samples (n = 866). Kirby–Bauer disk-diffusion test, a standard technique, was used to perform antibiotic susceptibility testing. Class 1 integron genes in P. aeruginosa were identified using the polymerase chain reaction. Results: The antibiotic resistance rate ranged between 19–100% for 184 isolates of P. aeruginosa tested. Polymerase chain reaction amplification revealed that 46.73% (86/184) of P. aeruginosa strains carried Class 1 integron gene, that strains also showed resistance to majority of the antibiotics tested. Negatively, most of the Class 1 integron genes were isolated from wound infections (n = 45) than burn infections (n = 41). Conclusion: The current study revealed that P. aeruginosa isolates that carrying Class 1 integron possess higher level of resistance to amoxicillin, ceftazidime, aztreonam, meropenem, tobramycin, piperacillin, gentamicin, ciprofloxacin, and netilmicin. Therefore, it is essential to conduct antibiotic surveillance and molecular epidemiological studies to practice effective empirical therapies across the hospital settings.

Key words: Antibiotics, infections, integron, multidrug resistant


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ali Hassoun Hammadi
Articles by Qutaiba Ahmed Al Khames Aga
Articles by Nabil Awni Nimer
Articles by Pottathil Shinu
Articles by Anroop B Nair
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. PNR. 2020; 11(1): 19-22. doi:10.4103/jpnr.JPNR_9_20

Web Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. https://www.pnrjournal.com/?mno=133358 [Access: August 12, 2022]. doi:10.4103/jpnr.JPNR_9_20

AMA (American Medical Association) Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. PNR. 2020; 11(1): 19-22. doi:10.4103/jpnr.JPNR_9_20


Vancouver/ICMJE Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. PNR. (2020), [cited August 12, 2022]; 11(1): 19-22. doi:10.4103/jpnr.JPNR_9_20


Harvard Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair (2020) Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. PNR, 11 (1), 19-22. doi:10.4103/jpnr.JPNR_9_20


Turabian Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. 2020. Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. Journal of Pharmaceutical Negative Results, 11 (1), 19-22. doi:10.4103/jpnr.JPNR_9_20


Chicago Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. "Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections." Journal of Pharmaceutical Negative Results 11 (2020), 19-22. doi:10.4103/jpnr.JPNR_9_20


MLA (The Modern Language Association) Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair. "Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections." Journal of Pharmaceutical Negative Results 11.1 (2020), 19-22. Print. doi:10.4103/jpnr.JPNR_9_20


APA (American Psychological Association) Style

Ali Hassoun Hammadi, Qutaiba Ahmed Al Khames Aga, Nabil Awni Nimer, Pottathil Shinu, Anroop B Nair (2020) Antimicrobial resistance and presence of Class 1 integrons in Pseudomonas aeruginosa isolates from burn and wound infections. Journal of Pharmaceutical Negative Results, 11 (1), 19-22. doi:10.4103/jpnr.JPNR_9_20


Author Login Reviewer Login About Publisher Editorial Policies Peer Review Policy Editorial & Peer Review Process Author's Rights and Obligations Publication Ethics and Publication Malpractice Statement Conflict of Interest Policy Plagiarism Policy Protection of Research Participants (Statement On Human And Animal Rights) Privacy Policy Publication Ethics and Publication Malpractice Statement Corrections, Retractions & Expressions of Concern Self-Archiving Policies Statement of Informed Consent Advertising Policy Terms of Use License Information Copyright Information
This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.
The articles in Journal of Pharmaceutical Negative Results are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Copyright © 2022 Journal of Pharmaceutical Negative Results All Rights Reserved. Subject to change without notice from or liability to Journal of Pharmaceutical Negative Results.
For best results, please use Internet Explorer or Google Chrome

Contact Information


  ResearchTrentz

 Scientific Research Community 

Contact US

21, First Floor,ResearchTrentz (Registred Office)
                          Thamotharan Street,India

 Email : editorial@pnrjournal.com, Support : pnrjournal@gmail.com