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ORIGINAL ARTICLE
Year : 2011  |  Volume : 2  |  Issue : 2  |  Page : 55-57

Lack of antiglycation activity of fresh juice of whole plant of Enicostema axillare (Lam.) Raynal


1 Department of Zoology, University of Colombo, Colombo, Sri Lanka
2 Department of Nidana Chikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka
3 Herbal Technology Section, Industrial Technology Institute, Colombo, Sri Lanka

Correspondence Address:
W D Ratnasooriya
Department of Zoology, University of Colombo, Colombo 3
Sri Lanka
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9234.90210

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Objective: To investigate the antiglycation potential of fresh juice of whole plant of Enicostema axillare (Lam.) Raynal. in vitro. Materials and Methods: Antiglycation activity of fresh juice of whole plant was determined in vitro using five concentrations (25, 50, 100, 200, and 400 μg/ml) by determining their ability to inhibit the formation of advanced glycation endproducts in a bovine serum albumin / glucose system using fluorescence spectroscopy. Results: There is no antiglycation activity in vitro of fresh juice of E. axillare plant. Conclusion: It is unlikely that impairment of diabetic complications by E. axillare whole plant juice as claimed by ayurvedic and traditional physicians is mediated via antiglycation activity.


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