Advertisment ACS-IndiaSymposium
 
Journal of Pharmaceutical Negative Results
  Print this page Email this page Small font sizeDefault font sizeIncrease font size 
Search Article 
  
Advanced search 
 Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts  
 
ORIGINAL ARTICLE
Year : 2012  |  Volume : 3  |  Issue : 1  |  Page : 22-25

Lack of analgesic property in xanthium strumarium Linn. Fruit's butanolic extracts


Department of Pharmacology , Shri Ram Institute of Technology, Jabalpur, Madhya Pradesh, India

Correspondence Address:
Shashi Bharti Shukla
Dhanwantri Nagar, Jabalpur, Madhya Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9234.99643

Rights and Permissions

Objective: The objective of the present study is to investigate the analgesic activity profile of xanthium strumarium Linn. (Family: Asteraceae) in mice and rats, using various models. Materials and Methods: The effects of the butanolic extract were observed in three different dose levels 50, 100, and 150 mg / kg, as the extract did not show any sign of toxicity up to 500 mg / kg (p.o.) dose. The investigation was carried out for assessing the activity on thermal and chemical-induced pain reactions. Result: The Xanthium strumarium (XS) fruit's butanolic extract did not have any significant effect on the thermal pain reaction (hot plate method). The extract was devoid of any protective effect against acetic acid-induced writhing, at any of the tested doses. Conclusion: The Xanthium strumarium Fruits' butanolic extract lacked analgesic activity.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2894    
    Printed224    
    Emailed1    
    PDF Downloaded397    
    Comments [Add]    

Recommend this journal