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Journal of Pharmaceutical Negative Results
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ORIGINAL ARTICLE
Year : 2013  |  Volume : 4  |  Issue : 1  |  Page : 1-4

Lack of brine shrimp lethality and hemagglutination activity in Grewia asiatica Linn


1 Department of Pharmacy, Hazara University, Havelian Campus, Abbottabad, Pakistan
2 Department of Genetics, Hazara University, Mansehra, Pakistan
3 Department of Horticulture, Faculty of Agriculture, Gomal University, Dera Ismail Khan, Pakistan

Correspondence Address:
Abidah Parveen
Department of Pharmacy, Hazara University, Havelian Campus, Abbottabad 22010
Pakistan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9234.116754

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Objective: To investigate the brine shrimp lethality and hemagglutination activity of the fruit, stem bark and leaves of Grewia asiatica L. (Family: Tiliaceae). Materials and Methods: The crude ethanolic extracts and fractions of the fruit, stem bark, and leaves were subjected to cytotoxic assay using brine shrimps and were also investigated for hemagglutination activity. Results: Brine shrimps survived easily and hemagglutination activity was not observed. Conclusions: The fruits, leaves and stem bark of G. asiatica have insignificant brine shrimp lethality and hemagglutination activity was found to be absent.


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