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Journal of Pharmaceutical Negative Results
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ORIGINAL ARTICLE
Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 1-3

Absence of anthelmintic activity of hydroalcoholic leaf extracts of Artabotrys hexapetalus (Linn.f)


1 Department of Horticulture, University of Agriculture Sciences (UAS[B]), Gandhi Krishi Vignan Kendra, Bellary Road, Karnataka, India
2 Department of Biotechnology, Sapthagiri College of Engineering, Hessaghata Main Road, Bangalore, Karnataka, India

Correspondence Address:
M Vasundhara
Department of Horticulture, UAS (B), Gandhi Krishi Vignan Kendra, Bellary Road, Bangalore 560 065, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9234.136770

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Objective: To study the anthelmintic activity of Artabotrys hexapetalus (Linn.f) leaves. Materials and Methods: The extraction was made using the hydroalcohol with soxhlet extraction system. The hydroalcoholic extract of varying concentration was used for conducting anthelmintic activity (12.5, 25, 50 and 100 mg/ml). Eudrilus eugeniae (African adult earthworm) was used as the test organism. Result: The time of paralysis and death of the earthworms, the positive control (albendazole) was more effective and no effect was shown by the hydroalcoholic extract of varying concentrations. Conclusion: Hydroalcoholic extract of Artabotrys hexapetalus, didn't show any anthelmintic activity at the concentration of 12.5, 25, 50 and 100 mg/ml.


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