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Journal of Pharmaceutical Negative Results
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Year : 2014  |  Volume : 5  |  Issue : 1  |  Page : 29-33

Insignificant influence of test order on cognitive behavior in Wistar rats

Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Correspondence Address:
Mohd Makmor-Bakry
Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300
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Source of Support: Universiti Kebangsaan Malaysia (FRGS/1/2012/ SKK02/UKM/02/2)., Conflict of Interest: None

DOI: 10.4103/0976-9234.136790

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Objectives: The aim was to evaluate the effects of test order in behavioral performance of Wistar rats in cognitive performance tasks. Materials and Methods: The rats were tested with both object recognition and object location tasks in different test orders with an inter-test interval of 1-day. Results: An open field box sized 60 × 60 × 40 cm was associated with better experimental outcome compared with box sized 100 × 100 × 50 cm. Test order has insignificant effects on the exploration activity of rats with the 1-day inter-test interval. Conclusion: Test order of the cognitive performance tasks with inter-test interval of 1-day did not influence the performance of Wistar rats.

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