Advertisment ACS-IndiaSymposium
 
Journal of Pharmaceutical Negative Results
  Print this page Email this page Small font sizeDefault font sizeIncrease font size 
Search Article 
  
Advanced search 
 Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts  
 
ORIGINAL ARTICLE
Year : 2017  |  Volume : 8  |  Issue : 1  |  Page : 25-30

Effectiveness of photodynamic therapy and probiotics as an adjunct to scaling and root debridement in the treatment of chronic periodontitis


Faculty of Dentistry, SEGi University, Selangor, Malaysia

Correspondence Address:
Srinivas S Ramachandra
Faculty of Dentistry, SEGi University, No. 9, Jalan Teknologi, Taman Sains, Kota Damansara, Selangor
Malaysia
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0976-9234.204908

Rights and Permissions

Objective: This study aimed to evaluate the effectiveness of a single application of photodynamic therapy (PDT) and probiotics as an adjunct to scaling and root debridement (SRD) to treat chronic periodontitis. The objectives of the study were to compare the probing pocket depths and clinical attachment loss (CAL) in experimental sites (E-sites) treated with PDT and probiotics with SRD against SRD alone (controls) at the baseline and 3 months post intervention. Materials and Methods: In 22 chronic periodontitis patients aged 25–45 years, 136 sites with pocket depths of 4–6 mm were identified. In each patient, one E-site was randomly selected while one served as control. E-sites were treated with SRD + PDT + probiotics whereas control sites received only SRD. Clinical parameters of pocket depths and CAL were measured at the baseline and at 3 months. Results: In the E-sites, mean pocket depth was 3.62 ± 1.40 mm at the baseline and 3.12 ± 1.48 mm after 3 months. In the control sites, the mean pocket depth was 3.43 ± 1.46 mm at the baseline and 2.99 ± 1.45 after 3 months. In the E-sites, the mean CAL before treatment was 5.31 ± 1.39 mm and 5.10 ± 1.46 mm after treatment. In the control sites, mean CAL before treatment was 5.15 ± 1.41 mm and 4.87 ± 1.55 mm after treatment. There was no significant improvement in pockets depths and CAL between the E-sites and control sites. Conclusion: A single application of PDT + probiotics with SRD did not show any additional clinical benefits when compared with SRD alone. Further studies with multiple applications of PDT and probiotics are needed.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed987    
    Printed28    
    Emailed0    
    PDF Downloaded83    
    Comments [Add]    

Recommend this journal