Journal of Pharmaceutical Negative Results

ORIGINAL ARTICLE
Year
: 2016  |  Volume : 7  |  Issue : 1  |  Page : 16--20

Insignificant antifungal activity of plant extracts on Malassezia furfur


Sreelatha Gopalakrishnan Lalitha, Lakshmeesha Thimappa Ramachandrappa, Soumya Krishnamurthy, Jayashree Basavaraju, Sharmila Thirumale 
 Department of Microbiology and Biotechnology, Jnanabharathi Campus, Bangalore University, Bengaluru, Karnataka, India

Correspondence Address:
Sharmila Thirumale
Department of Microbiology and Biotechnology, Jnanabharathi Campus, Bangalore University, Bengaluru - 560 056, Karnataka
India

Objective: The aim of present study was to investigate the antimalassezial potential of the selected plant extracts known to possess medicinal values. Materials and Methods: The crude extracts of five botanicals were evaluated against Malassezia furfur. The dried and pulverized plant material was extracted with water and also successively extracted with hexane, chloroform, and methanol, using the Soxhlet apparatus. The antimicrobial activity assay was done by disk diffusion and 96-well plate microdilution method. Results: The results point toward the fact that all the tested extracts extracted in solvents of different polarities exhibited no antifungal activity. Conclusion: The tested extracts did not have, or had too little, antifungal activity to be used as a promising source of novel antimicrobial substances against M. furfur.


How to cite this article:
Lalitha SG, Ramachandrappa LT, Krishnamurthy S, Basavaraju J, Thirumale S. Insignificant antifungal activity of plant extracts on Malassezia furfur.J Pharm Negative Results 2016;7:16-20


How to cite this URL:
Lalitha SG, Ramachandrappa LT, Krishnamurthy S, Basavaraju J, Thirumale S. Insignificant antifungal activity of plant extracts on Malassezia furfur. J Pharm Negative Results [serial online] 2016 [cited 2019 Oct 21 ];7:16-20
Available from: http://www.pnrjournal.com/article.asp?issn=0976-9234;year=2016;volume=7;issue=1;spage=16;epage=20;aulast=Lalitha;type=0