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  Indian J Med Microbiol
 

Figure 2: Effect of KYP-2047 on the inhibition of trypanosome and human prolyl oligopeptidase activity. Cell extracts of bloodstream forms of Trypanosoma brucei (circles) and human myeloid leukemia HL-60 cells (squares) were incubated with varying concentrations of KYP-2047. After 30 min incubation, the prolyl oligopeptidase activity was measured using the fluorogenic peptide substrate Suc-Gly-Pro- Leu-Gly-Pro-AMC. The experiment was repeated 3 times and mean ± standard deviation are shown

Figure 2: Effect of KYP-2047 on the inhibition of trypanosome and human prolyl oligopeptidase activity. Cell extracts of bloodstream forms of <i>Trypanosoma brucei</i> (circles) and human myeloid leukemia HL-60 cells (squares) were incubated with varying concentrations of KYP-2047. After 30 min incubation, the prolyl oligopeptidase activity was measured using the fluorogenic peptide substrate Suc-Gly-Pro- Leu-Gly-Pro-AMC. The experiment was repeated 3 times and mean ± standard deviation are shown