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  Indian J Med Microbiol
 

Figure 2: Absence of antiviral activity of rutin after Mayaro virus infection (moi 0, 1). Viral cytopathic effect in Vero cells. (a) Cellular control: untreated and uninfected cells; (b) viral control: infected and untreated cells; (c) vehicle control: Infected and treated cells with 0.2% (v/v) DMSO; (d) rutin treated (500 μg/mL) and infected cells; and (e) positive control: Ribavirin treated (200 μg/mL) and infected cells. The cytopathic effect reduction was observed only in ribavirin when compared to viral control. Black arrows indicate some clusters of cells from the cytopathic effect of the Mayaro virus (×100)

Figure 2: Absence of antiviral activity of rutin after <i>Mayaro virus</i> infection (moi 0, 1). Viral cytopathic effect in Vero cells. (a) Cellular control: untreated and uninfected cells; (b) viral control: infected and untreated cells; (c) vehicle control: Infected and treated cells with 0.2% (v/v) DMSO; (d) rutin treated (500 μg/mL) and infected cells; and (e) positive control: Ribavirin treated (200 μg/mL) and infected cells. The cytopathic effect reduction was observed only in ribavirin when compared to viral control. Black arrows indicate some clusters of cells from the cytopathic effect of the <i>Mayaro  virus</i> (×100)