Anticataleptic And Antiepileptic Activity Of Ethanolic Extract Of Leaves Of Morinda Reticulate : A Study On Role Of Dopaminergic System In Epilepsy In Albino Rats

Authors

  • Susmitha uppugalla , Chiranjib Bhattacharjee , Arunabha Mallik , N Sriram , G Sumithira , S Kameshwaran , S Sathya

DOI:

https://doi.org/10.47750/pnr.2022.13.S09.616

Abstract

In this study is to assess the anticataleptic and antiepileptic activity of leaves of Morinda reticulate in albino rats. Haloperidol-induced catalepsy (HIC), maximum electro-shock (MES) method, pilocarpine-induced Status epilepticus (PISE) and single-dose effect of M. reticulate were employed. M. reticulate (100 mg/kg) had significant anticataleptic and antiepileptic activity in HIC, MES, and PISE. M. reticulate extract has the potential to be an anticataleptic and antiepileptic drug. Dopamine and 5-HT may have a role in such activity.

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Published

2022-12-10 — Updated on 2022-12-10

Versions

Issue

Vol. 13 SPECIAL ISSUE 09 (2022)

Section

Articles

How to Cite

Anticataleptic And Antiepileptic Activity Of Ethanolic Extract Of Leaves Of Morinda Reticulate : A Study On Role Of Dopaminergic System In Epilepsy In Albino Rats. (2022). Journal of Pharmaceutical Negative Results, 4987-4991. https://doi.org/10.47750/pnr.2022.13.S09.616