A CROSS SECTIONAL STUDY TO ASSESS TRIGLYCERIDE GLUCOSE INDEX AND TRIGLYCERIDE/HDL RATIO AS POTENTIAL INDICATORS OF GLYCEMIC CONTROL IN TYPE 2 DIABETES MELLITUS
DOI:
https://doi.org/10.47750/pnr.2023.14.02.266Abstract
Introduction: The treatment strategy for management of Diabetes Mellitus includes regular monitoring of blood sugars and HbA1C since poor glycemic control is associated with complications causing significant morbidity and mortality.
Aim: To assess the correlation of Triglyceride glucose Index and Triglyceride/HDL ratio with HbA1C to evaluate their possible role as indicators of glycemic control in Type 2 Diabetes Mellitus.
Objectives: To correlate Triglyceride glucose index and HbA1C in patients with Type 2 Diabetes Mellitus.
To correlate triglyceride/HDL-C ratio and HbA1C in patients with Type 2 Diabetes Mellitus.
To evaluate the role of triglyceride glucose index and Triglyceride/HDL-C ratio as potential indicators of glycemic control.
Materials and Methods: A retrospective cross-sectional study was carried out in our Institution among 278 patients with Type 2 Diabetes Mellitus. The necessary biochemical parameters along with history of comorbidities will be noted. The Triglyceride glucose index and Triglyceride/HDL ratio was calculated, and statistical analysis was carried out to correlate the calculated values and HbA1c.
Results: Triglyceride glucose index and Triglyceride/HDL ratio were found to be significantly associated with HbA1c levels in patients with type 2 diabetes mellitus (Pearson correlation coefficient of 0.475 and 0.276 respectively). Triglyceride glucose index is significantly associated with glycemic control (t value -3.627) while Triglyceride/HDL ratio did not show significant association (t value -1.556).
Conclusion: In patients with Type 2 Diabetes mellitus the Triglyceride glucose index is significantly associated with glycosylated hemoglobin (HbA1c) levels and is a potential predictor glycemic control. Triglyceride/HDL ratio is significantly associated with HbA1c levels but failed to show significant association with glycemic control.
