Evaluation Of Zinc, Magnesium And Glycated Hemoglobin In The Individuals Affected With Psoriasis

Abstract

Background: People with autoimmune diseases like psoriasis are unlikely to find a natural treatment that is powerful enough to make up for the pathophysiological abnormalities that have developed. Aim: The aim of the present study is to compare and correlate the association of zinc, magnesium, and glycated hemoglobin in the individuals affected with psoriasis and the non-psoriasis controls. Materials & methods:  Four hundred (400) individuals participated in the current study, divided evenly between the psoriasis group and the healthy control group. Utilizing the outpatient services of the Index Medical College and Research Center in Indore, examinations were conducted on each and every participant in both groups. After receiving green light from the institution's ethics board, the authors of the study proceeded with the project. Results: We tried to find the association between the serum levels of zinc and MDA in healthy controls.  We observed a negative association (y = -0.0247 + 27.236) between serum zinc and MDA; zinc and HbA1c (y = -0.05035x + 5.868) in non-psoriasis control group. Conclusion: The fact that persons with psoriasis have lower levels of zinc transporters than people who do not have psoriasis is the root cause of this imbalance. According to the findings of this study, there is a correlation between having psoriasis and having altered levels of zinc and magnesium levels in the body.