To Determine The Prevalence Of Pseudomonas Aeruginosa And The Antibiotic Sensitivity Profile Of This Organism In Post-Operative Wound Infections

Abstract

Aim: The aim of this study was to determine the prevalence of Pseudomonas aeruginosa and the antibiotic sensitivity profile of this organism in post-operative wound infections in a tertiary care hospital.

Materials and Methods: Aerobic processing was performed on the clinical specimens that were obtained in the form of post-operative wound swabs. All of the samples were microscopically inspected using Gram and Zeihl Nelsen staining, and they were concurrently cultivated on blood agar, MacConkey agar, and nutritional agar medium. The results of these tests were compared. After an aerobic incubation at 37 degrees Celsius for 16-18 hours, the media plates were readied for use.

Results: The post-operative patients who were admitted to the hospital all provided a total of 80 wound swabs, which were collected. Ninety percent of the samples showed signs of growth, whereas ten percent of the samples were sterile. In 25% of the samples, Pseudomonas aeruginosa was discovered. This was followed by Escherichia coli in 21.25% of the samples, Klebsiella pneumonia in 18.75% of the samples, Staphylococcus aureus in 17.5% of the samples, Proteus mirabilis in 3.75% of the samples, and Acinetobacter baumannii in 1.25% of the samples. There was evidence of mixed infection in 2.50 percent of the samples. The antibiotic colistin showed the greatest degree of effectiveness against P. aeruginosa (95 percent), followed by meropenem (75 percent) and imipenem (75 percent).

Conclusion: Pseudomonas infection was depending on age, sex, and even period of stay in the hospital. In order to forestall the development of additional forms of antibiotic resistance, it is essential for individual health care settings to implement surveillance programs, formulate antibiotic policies, and implement infection control practices.