Comparative Study Of Synthetic Antibiotic Amoxicillin With Volatile Oil Extracted From Some Traditional Medicinal Plants On Bacteria Human Pathogen (Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli)

Abstract

The extensive utilization of antibiotics in clinical practice, agriculture, and veterinary settings contributes to the emergence of antibiotic resistance in infectious microorganisms. This escalating problem poses a significant challenge in effectively treating pathogenic microbes. The study assessed the comparative antibacterial effects of Amoxicillin, a modern drug, and various essential oils against both Gram-positive (S. pyogenes and S. Aureus) and Gram-negative (P. aeruginosa and E. coli) bacteria. Amoxicillin exhibited moderate inhibition, while essential oils, including Basil and Eucalyptus, showed variable effects. Basil oil displayed limited inhibition against S. pyogenes but strong inhibition (21 mm) against S. aureus. Eucalyptus oil demonstrated limited inhibition against S. pyogenes, strong inhibition (19 mm) against S. aureus, and moderate inhibition against P. aeruginosa. Cypress oil effectively inhibited S. aureus (20 mm) but was ineffective against other bacteria. Notably, Dill oil demonstrated robust inhibitory effects, especially against S. pyogenes (16 mm), S. aureus (18 mm), and P. aeruginosa (15 mm), with moderate inhibition against E. coli (13 mm). The study underscores the potential of essential oils, particularly Dill oil, as viable alternatives or supplements to traditional antibiotics, emphasizing their diverse antibacterial properties.