METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF ELEMENTAL IMPURITIES IN MEDROXYPROGESTERONE TABLETS 10mg BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY

Authors

  • Jerri P Venkata Krishna
  • S. Rajasekaran

DOI:

https://doi.org/10.47750/pnr.2022.13.S06.154

Keywords:

Medroxyprogesterone tablets 10mg, ICPMS, Method development, Method Validation, of Cadmium, Lead, Arsenic, Mercury, and Lithium.

Abstract

The analytical method development and validation of Medroxyprogesterone tablets 10mg summarizes the outcome of the results for content of Cadmium, Lead, Arsenic, Mercury, and Lithium in by ICP-MS1. The test sample was prepared with microwave assisted acid digestion and introduced into optimized instrumental parameters for use of a quadruple based Agilent 7700 inductively coupled plasma mass spectrometry instrument. This method development and validation by ICP-MS to prove that it is Specific, Precise, Accurate, Linear, Robust, Reproducible and Capable of producing reliable results.

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Published

2022-10-10

Issue

Vol. 13 SPECIAL ISSUE 06 (2022)

Section

Articles

How to Cite

METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF ELEMENTAL IMPURITIES IN MEDROXYPROGESTERONE TABLETS 10mg BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY. (2022). Journal of Pharmaceutical Negative Results, 1167-1178. https://doi.org/10.47750/pnr.2022.13.S06.154