A Review On Drug Discovery And Development
DOI:
https://doi.org/10.47750/pnr.2022.13.S05.344Keywords:
Lead compound, hit discovery, clinical phase, pre-clinical phase, and adverse reaction.Abstract
Developing and discovery of a new drug for treating a disease is costly and needs up to 14 year’s research and testing. Proper procedure
necessitates a stepwise approach along with well documentation. Normally the work starts with target identification and validation.
Optimization, discovery of lead compounds and testing on animals in pre pre-clinical phase are different stages which need to be
followed by clinical studies and assessing the drug candidates on humans. Approximately every one to ten drug candidates may have
a chance to be marketed. After marketing, development still continues by evaluation and study of adverse reactions or finding new
action of drugs which was not recognized before. In this research, all mentioned steps briefly have been reviewed.
