Comparison Of Epicardial Adipose Tissue Thickness And Anthropometric Measurement In Metabolic Syndrome

Abstract

Background: Epicardial tissue thickness is component of visceral adipose tissue. Abdominal fat increases with obesity in Metabolic Syndrome & 2D-ECHO is cheaper, non-invasive modality to measure epicardial adipose tissue thickness. Present study aimed for comparison of epicardial adipose tissue thickness and anthropometric measurement in patients with metabolic syndrome.

Material & Method: This comparative study was conducted among the patients attending the OPD of Department of General Medicine, AVMCH. Patients were grouped as cases and controls. Study was done over a period of two years on cases i.e hospitalized adults with the diagnosis of metabolic syndrome {The individuals satisfying criteria given by International diabetic Federation } & also on controls i.e patients coming for health check-up which may not fit in criteria of metabolic syndrome in Department of General Medicine, AVMCH. After informed & written consent from the patients, detailed history, clinical assessment & laboratory investigations were done.

Result: The overall mean of age of the participants was found to be 43.57±11.32yrs, among them 39.8% were female and 60.2% were male. Mean central waist circumference, SBP, DBO, TG, FBS, 2D-ECHO long axis (mm), and 2D-ECHO short axis (mm) was found to be significantly higher among the cases compared to control and HDL was found to be significantly lower. There is a significant positive strength of association of central obesity, TG, SBP and DBP with 2D-ECHO long and short axis thickness and negative relation with HDL cholesterol.

Conclusion: The present study documented a significant strength of correlation between epicardial adipose tissue thickness with the anthropometric measurements in patients with metabolic syndrome.