Polymers Use In Mouth Dissolving Formulation: A Review Article

Abstract

Technology advancements in recent years have made effective dose alternatives to the oral route for patients who are young,old, immobile, queasy, or unable to comply. Fast-dissolving oral thin film is a solid dosage form, which disintegrate or dissolve within 1 min when placed in the mouth without drinking of water or chewing. Oral fillm includes various ingredients for its formulation which includes polymers, active pharmaceutical ingredient, film stabilizing agents, sweeteners, flavours, colors, saliva stimulating agents, preservatives, surfactants etc but the first and far most a very essential ingredient which helps in film formation is a Polymer. Fast dissolving Film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via dissolution when contact with liquid is made. For quickly disintegrating films, wafter-soluble polymers are utilised as film formers.T watersoluble polymers give the films quick disintegration, a pleasant mouthfeel, and mechanical qualities.