THE EFFECT OF SOME ANIMAL AND PLANT PROTEINS ON CREATININE INDEX IN RAT WITH ACUTE RENAL FAILURE

Abstract

Kidney diseases are public health problem all over the world. From recent studies it has been found that a low-protein diet as part of diet therapy has beneficial effects that slow the progression of chronic kidney disease. So, this study was carried out to investigate the creatinine index of some animal protein (Camel meat, rabbit meat, Tilapia) and plant protein (Popcorn, brown lentils, chickpeas) in rats with induced-acute renal failure (ARF). Forty rats weighing approximately 170-180 g, were divided into 8 groups (n=5) in each group. The first group of rats (normal) was fed on basal diet. The ARF rats were divided into 7 groups, one of which was a positive control group and fed on basal diet until the end of the experiment. The rest of the groups were fed on basal diet fortified with 150 g of dry powder meat of camel, rabbit, tilapia, popcorn, brown lentils and chickpeas, respectively. The treated groups with either animal or plant proteins had a significant decrease (P<0.05) in the level of kidney functions parameters as well as lowering the mean values of PO₄, Na and K. The level of serum albumin and total protein were significantly (P<0.05) increased as compared to the positive control group. It could be concluded that a diet containing animal protein (Camel meat, rabbit meat, Tilapia) and plant protein (popcorn, brown lentils, chickpeas) may be used as a part of diet therapy to slow the progression of kidney disease. These diets may be beneficial for patients who suffer from acute renal failure.