ABOUT RESEARCHES OF TECHNOLOGY OF PREPARATION OF INFUSION SOLUTION "PHOSPHARGININE SUCCINATE"

Abstract

To date, metabolic drugs are widely used in the treatment of cardiovascular diseases, and there is a great demand for these drugs in our republic. Model compositions and technology of solutions for infusions of Phospharginine succinate containing fructose-1,6-diphosphate, L-arginine hydrochloride and succinic acid have been developed, which are subsequently recommended for industrial production at the local enterprise “TEMUR MED PHARM” LLC. Theoretical calculations were carried out and the current osmotic concentrations (osmolarity, milliosmol (mosm)) and pH values of infusion solutions were established.