Synthesis Of New Propargyl Ester Derivatives And Biostimulation Activity Of 4-(Bis(2-Hydroxyethyl)Amino)But-2-Yn-1-Yl Butyrate

Abstract

The proposed article relates to synthesis and the study of new propargyl ester derivatives, and biostimulation activity of 4-(bis(2-hydroxyethyl)amino)but-2-yn-1-yl butyrate. Aminomethylation reactions of the obtained propargyl ester with ethanolamine and paraform were carried out in the presence of a catalyst. Copper salts were used as a catalyst. The structure of the new propargyl ester derivatives was established by IR and ¹Н-, ¹³C- NMR spectroscopy. Comparative tests show that the test derivative of the drug 4-(bis(2-hydroxyethyl)amino)but-2-yn-1-yl butyrate showed a higher growth-promoting activity.