SYNTHESIS OF ECOFRIENDLY SILVER NANOPARTICLES USING MANGROVE ASSOCIATE PLANT PEMPHIS ACIDULA J.R.FORST & FORST EXTRACT: ANTIOXIDANT AND ANTIINFLAMMATORY STUDIES

Abstract

The current study is to advance an easy and eco-friendly method for the synthesis of AgNPs using aqueous whole plant extract of mangrove associate plant Pemphis acidula.  This study also evaluated its antioxidant and antiinflammatory activity. The presence of flavonoids, phenols, terpenoids, saponins, tannins, glycosides and xanthoproteins were settled by the phytochemical analysis of the plant aqueous extract. These chemicals can be used as reducing, stabilizing and capping agents. The PA-AgNPs were characterized by UV-Vis spectrophotometry, XRD, FTIR, SEM  and AFM. AgNPs formation was checked by UV-Vis spectra at 428.5 nm. FTIR had shown that the phytochemicals were accountable for the reduction and capping material of silver nanoparticles. The size and shape of the AgNPs were regulated using SEM. The XRD results disclosed a crystalline nature of AgNPs with an average size of 30.24nm. The surface morphology was approved by AFM techniques. The PA-AgNPs had revealed strong antioxidant (DPPH, H₂O₂ scavenging) action. The PA – AgNPs displayed strong antiinflammatory (albumin denaturation, proteinase inhibitory) activity. To our best knowledge, this is the first effort on the synthesis of AgNPs by mangrove associate plant Pemphis acidula whole extract. Lastly, it can be accomplished that PA-AgNPs from Pemphis acidula whole plant extract showed distinguishing antioxidant and antiinflammatory action.