A Comparative Study Of Free Psa In Women With Malignant Breast Disease And Normal Women At A Tertiary Care Centre

Abstract

Measurement of PSA has potential uses for the treatment of breast cancer in women.  Total and free PSA levels in women with breast cysts, uterine fibroids, and breast cancer be fore and six months after surgery are significantly higher versus a control group of healthy women. Women with breast cancer have significantly higher detectable total PSA before surgery than after and serum-free PSA was associated  with a higher histologic grade of breast cancer.

As the PSA level detected in a woman’s saliva equaled serum PSA levels throughout  a woman’s menstrual cycle, thus, PSA may be used as a tool for detection and play a  role in monitoring treatment response and surveillance for tumour progression and  metastasis. Therefore, PSA values may eventually help clinicians detect breast disease  and differentiate higher-and lower-risk cancers.