Comparative Evaluation of Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Diamine Fluoride with Potassium Iodide on Candida albicans and Lactobacilli Count and Effect on Salivary pH in Children– An In-Vivo Study

Abstract

Background : Dental caries is described as the localized destruction of susceptible dental hard tissues caused by acidic byproducts of microbial fermentation of dietary carbohydrates. Aim :- The aim of this study is to evaluate and compare the
efficacy of Silver Diamine Fluoride and the combination of Silver Diamine Fluoride with Potassium Iodide on the Candida
albicans and Lactobacillus count and pH of saliva in children with carious deciduous molars. Method: The study involved 60
children from the age group of 3 to 9 years were randomly divided into 2 groups, Group I- Silver Diamine Fluoride and Group
II- Silver Diamine Fluoride and Potassium Iodide. Each group was further divided into subgroups of Candida albican and
Lactobacilli Group. The Saliva samples were collected from each candidate before and after the application of the material to
check the microbial count as well as the pH of the saliva as a baseline value. The post application saliva collection as well as pH
check was done at the interval of Immediate after the application, 1 week, 1month and 3 months. The results obtained were
analysed using ANOVA, and student t test.Result: The pH of the saliva was increased after the application of both the
materials and was effective till 3 months. Both the materials were effective in decreasing the microbial count.Conclusion: The
result of the study confirms that both Silver Diamine Fluoride and Silver Diamine Fluoride and Potassium iodide have
antimicrobial effect on both Candida albican and lactobacilli species.