A REVIEW ON THE PHARMACEUTICAL ANALYTICAL PROFILE OF AN ANTIVIRAL DRUG: REMDESIVIR
DOI:
https://doi.org/10.47750/pnr.2022.13.S09.026Keywords:
Remdesivir, HPLC, LC/MS, UV-Visible spectroscopy, Fluorometry.Abstract
Remdesivir is a prodrug that works by imitating the nucleoside adenosine. It is an antiviral medication that has been used to treat the coronavirus. Given the severity of the condition, the medicine is critical to the therapy and accompanying research. Remdesivir is extremely important as a medicinal dose form. Remdesivir has been used with other medications in the following combinations: Remdesivir and Dexamethasone, Remdesivir and Tocilizumab, and Remdesivir and Ivermectin. To aid future study, the paper also gives a simultaneous and comparative review of the analytical investigations published in the literature for a pharmacological estimate. The extensive literature searches turned up a plethora of study publications. A complete explanation of common, hyphenated, and unique ways of analysis is given. Remdesivir analytical quantification is provided using HPLC, LCMS, UV-Visible spectroscopy, and fluorescence.