Spectral Characterization And Biological Screening Of 1,2,4-Triazole Derivatives Of Isothiocyanates

Abstract

Triazoles are the heterocyclic compounds having Nitrogen as heteroatoms with carbon. These are of 2 types on the basis of position of heteroatoms in five membered rings. Among which 1,2,4-triazole has been studied much in last decades due to its excessive antimicrobial activities. In this research work N-substituted derivatives of 1,2,4-triazole are prepared with the combination of substituted siothiocyanates and sodium hydroxide. The synthesized compounds were tested for their antimicrobial properties against bacteria E.coli, B.subtillis and fungus A.niger, P.chrysogenum. The compounds revealed moderate to high biological activities.