Synthesis, Characterization, Antimicrobial And Anticancer Evaluation Of (E)-2-(Benzylideneamino)-4-Methyl-N-(4-Oxo-2-(Substituted Phenyl)Thiazolidin-3-Yl)Thiazole-5-Carboxamide Derivatives

Abstract

Thiazolidinone derivatives (T1-T20) were synthesized and structures of these compounds were elucidated by IR, and ¹H NMR. Synthesized compounds were screened for antibacterial activity against Gram-negative (E. coli) and Gram-positive (S. aureus and B. subtilis) bacteria, antifungal activity against pathogenic fungal strains (A. niger and C. albicans and anticancer activity. Some of the compounds exhibited promising antimicrobial and anticancer activity.