Spectrum Of Neuroblastictumors : A Case Series With Review Of Literature

Abstract

Neuroblastic tumors represent a spectrum of disease from undifferentiated, aggressive type to the well differentiated, quiescent type. Based on the degree of differentiation, they are classified by International Neuroblastoma Pathology Committee into neuroblastoma, ganglioneuroblastoma and ganglioneuroma. These tumors are mainly seen in paediatric age group with adrenal being the most common site. However their occurrence in adults and at extra adrenal location is extremely rare. This case series reports 5 cases of neuroblastic tumors reported  over 18 months.  Three cases were adrenal while 2 were extra adrenal. The age range was from 1 year to 47 years, three of them being pediatric cases.  Male to female ratio was 3:2. Histopathology revealed 2 cases of neuroblastoma,2 ganglioneuroma and 1   ganglioneuroblastoma.