EXPERIMENTAL INVESTIGATION ON THE ORAL AND TOPICAL APPLICATION OF ALOE VERA IN WOUND CARE

Abstract

The inherent medicinal properties of Aloevera, has been deliberated on the wound healing process from centuries. The experimental and human evidences display the prompt utilization of the herb for several purposes like skin moisturizing, wound healing, frostbite and ischemic skin insults. The vasodilatory, anti-inflammatory, proliferative and antimicrobial actions were revealed in several experimental animal models in different invitro conditions. Accordingly prevailing studies explored substantial evidence for its clinical usefulness in wound care. The presented study has been motivated by the adorable characteristics of Aloe vera and investigated the topical and oral incorporation of the formulation briefly. For the purpose, 24 rats were categorized into four groups which are control, oral and topical (combined) treatment, oral treatment group and topical treatment group. After treatment the study compared the healing process within the four groups in terms of wound healing score, treatment alignment score, treatment maturity, vascularity and perivascular edema. The results revealed that combine effect of oral and topical formulation showed enhanced outcomes in nearing the normal stage. Hence the paper suggested that the integrated effect of oral and topical formulation will produce improved results in wound healing with aloe vera.