Frequency And Susceptibility Pattern Of Microorganisms Found In Surgical Site Infection

Abstract

Background

Surgical site wound infection is one of the serious concern in developing countries. Multiple studies have been done to find out the most commonly infecting bacteria and the susceptibility pattern, as it varies geographically, the type of surgery performed, the surgeon’s hand and hospital to hospital based on the status of sterilization. Current study aimed to find out the frequency and susceptibility pattern of microorganisms found in surgical site infection.

Methods: 

A descriptive cross-sectional study was conducted at the surgical department of Abbasi Shaheed hospital Karachi. The infected organism was identified by using culture test after that slide agglutination method was used to confirm it. Kirby Bauer disc diffusion technique was used to assess antibiotic sensitivity. The sensitivity of antibiotics tested were ampicillin, amoxicillin, augmentin, ceftriaxone, cefotaxime, ceftazidime, cefixime, cefepime, cefuroxime, amikacin, gentamycin, ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin, piperacillin in combination with tazobactam, meropenem and vancomycin. The results were analyzed by using Statistical Package for Social Science version 20.

Results:

The mean age of the study participants was 29.42 ± 9.2 years. Among all surgeries the infection rate was 13.9% while majority of cases were infected with E. coli (58.9%) after that staphylococcus aureus (14.7%) was found on second number. Antibiotic susceptibility pattern showed that the meropenem and piprecillin in combination with tazobactam were highly sensitive against E. coli and S. aureus with sensitivity of 97%, 94.1% and 89.2%, 75% respectively while vancomycin was highly sensitive against streptococci and S. aureus with sensitivity of 100% and 87.5% respectively.

Conclusion:

It can be concluded that postoperative wound infection is very common cause of morbidity in developing countries and E. coli was the most commonly involved organism. Antibiotic susceptibility pattern found the meropenem, piprecillin in combination with tazobactam and vancomycin as highly sensitive drugs.