Comparision Of Lymphocyte Monocyte Ratio With MELD And Child Pugh Scores In Cirrhosis Of Liver
DOI:
https://doi.org/10.47750/pnr.2022.13.S09.1291Abstract
BACKGROUND
In this study, we evaluated the lymphocyte monocyte ratio (LMR) with Model for End Stage Liver Disease (MELD) and Child-Pugh (CP) scores in cirrhosis of liver.
METHODS
This was a hospital based cross sectional study conducted among 85 patients who presented with liver cirrhosis to the Department of Medicine and Gastroenterology of jss hospital over a period of 18 months after obtaining clearance from Institutional Ethics Committee and written informed consent from the study participants.
STATISTICAL ANALYSISThe data collected were entered in MS excel 2010 and analysed using SPSS software IBM version 20
Descriptive Statistical measures like Percentage, Frequency, Mean, Standard deviation were calculated
RESULTS
Out of 85 patients, 10 were females and 75 were males. The minimum and maximum age was 27 and 76 years respectively, with the mean age being 53.22 ± 11.04 years. A total of 62.35% were affected by alcoholic liver disease. MELD and CP score showed positive correlation with significant p value (< 0.01), whereas LMR was negatively correlated to MELD and CP score with p value being insignificant.
CONCLUSION
In patients with liver cirrhosis, as the disease advances, LMR gets disrupted and decreases when compared with MELD and CP scores, which increase with disease progression. MELD and Child Pugh score requires both clinical and laboratory parameters to calculate and are cumbersome to calculate bedside.
